Pairing a cell-based reporter gene assay with Hermes high-content screening platform that provides the complete solution for a successful screening campaign for translocation of proteins from one cell compartment to another.
Protein translocation between cellular compartments is a key process in cell biology. A large variety of processes involve translocation, including signaling to modify cell function (e.g. gene expression), immune stimulation in viral infections and cargo transfer to and from the nucleus.
Imaging is a valuable approach to monitor the translocation process by visualizing the protein in the different compartments, measure its intensity and calculate the ratio of intensity of a labelled protein between the cytoplasmic and nuclear compartments as a quantitative measure of translocation.
This analysis performs measurement of the intensity ratio of a labeled protein between the cytoplasmic and nuclear compartments as a quantitative measure of translocation.
Pairing a cell-based reporter gene assay with Hermes high-content screening platform that provides the complete solution for a successful screening campaign for translocation of proteins from one cell compartment to another.
Protein translocation between cellular compartments is a key process in cell biology. A large variety of processes involve translocation, including signaling to modify cell function (e.g. gene expression), immune stimulation in viral infections and cargo transfer to and from the nucleus.
Imaging is a valuable approach to monitor the translocation process by visualizing the protein in the different compartments, measure its intensity and calculate the ratio of intensity of a labelled protein between the cytoplasmic and nuclear compartments as a quantitative measure of translocation.
This analysis performs measurement of the intensity ratio of a labeled protein between the cytoplasmic and nuclear compartments as a quantitative measure of translocation.
Automated image analysis, performed simultaneously with acquisition, identifies wells demonstrating high nuclear translocation upon treatment (red), in comparison to the low translocation measured in control wells (blue).
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Высококачественные автоматизированные решения
для визуализации клеток и анализа изображений
Поля помеченные * - обязательны для заполнения
Поля помеченные * - обязательны для заполнения
Поля помеченные * - обязательны для заполнения
